Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR1D | P28221 | 2/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9177848 | 0.84 | PTGS2 (0.44) | PTGS2PTGES2PTGDR2KMT2AKDM4E | |
| SCHEMBL23057137 | 0.70 | MCOLN2 (0.52) | PTGS2PTGES2KMT2AKDM4EPKM | |
| SCHEMBL10179841 | 0.69 | PTGS2 (0.48) | PTGS2PTGES2PTGDR2KMT2AKDM4E | |
| SCHEMBL20526580 | 0.69 | CA2 (0.50) | PTGS2 | |
| SCHEMBL7515266 | 0.68 | HSD17B10 (0.49) | PTGDR2KMT2ALMNAPOLBHDAC3 | |
| SCHEMBL9660227 | 0.68 | MCOLN3 (0.53) | PTGS2LMNAPOLB | |
| SCHEMBL27736700 | 0.68 | PTGDR2 (0.42) | PTGS2PTGDR2KMT2AKDM4EHDAC3 | |
| SCHEMBL3790323 | 0.68 | PTGDR2 (0.39) | PTGS2PTGES2PTGDR2KMT2AKDM4E | |
| SCHEMBL10814140 | 0.68 | ALDH1A1 (0.52) | ALOX15PTGDR2KMT2ATSHRLMNA | |
| SCHEMBL5821254 | 0.68 | PTGDR2 (0.46) | PTGS2PTGDR2KMT2ATSHRHTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5090964-A | Colorfastness, good exhaustion | CIBA-GEIGY CORPORATION (US) | 1992-02-25 | — | — | US | disclosed |