Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51052 | 0.89 | NR1H2 (0.46) | CA2HSP90AA1KCNH2NR1H2LMNA | |
| SCHEMBL1727399 | 0.87 | HSP90AA1 (0.47) | CA2HSP90AA1KCNH2NR1H2LMNA | |
| SCHEMBL51435 | 0.85 | CA2 (0.42) | CA2HSP90AA1KCNH2NR1H2LMNA | |
| SCHEMBL16859777 | 0.83 | CA2 (0.41) | CA2HSP90AA1KCNH2NR1H2LMNA | |
| SCHEMBL1835507 | 0.82 | LMNA (0.41) | CA2HSP90AA1KCNH2NR1H2LMNA | |
| SCHEMBL25738389 | 0.80 | CYP1A2 (0.43) | CA2HSP90AA1KCNH2NR1H2LMNA | |
| SCHEMBL9147326 | 0.80 | LMNA (0.46) | CA2HSP90AA1KCNH2NR1H2LMNA | |
| SCHEMBL10407904 | 0.79 | NR1H2 (0.55) | CA2HSP90AA1KCNH2NR1H2LMNA | |
| SCHEMBL11033935 | 0.79 | LMNA (0.42) | CA2HSP90AA1KCNH2NR1H2LMNA | |
| SCHEMBL7756021 | 0.79 | HSP90AA1 (0.41) | CA2HSP90AA1KCNH2NR1H2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5158925-A | Leuco dyes, color developer and isocyanuric acid dertivative | RICOH COMPANY, LTD. (JP) | 1992-10-27 | — | — | US | disclosed |