Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51435 | 0.92 | CA2 (0.42) | LMNACTDSP1HSP90AA1KCNH2CA2 | |
| SCHEMBL16859777 | 0.90 | CA2 (0.41) | LMNACTDSP1HSP90AA1KCNH2CA2 | |
| SCHEMBL9147326 | 0.87 | LMNA (0.46) | LMNACTDSP1HSP90AA1KCNH2CA2 | |
| SCHEMBL51052 | 0.84 | NR1H2 (0.46) | LMNACTDSP1HSP90AA1KCNH2CA2 | |
| SCHEMBL1324576 | 0.84 | LMNA (0.38) | LMNACTDSP1HSP90AA1KCNH2CA2 | |
| SCHEMBL1727399 | 0.82 | HSP90AA1 (0.47) | LMNACTDSP1HSP90AA1KCNH2CA2 | |
| SCHEMBL8617352 | 0.80 | LTA4H (0.49) | LMNACTDSP1NR1H2RAB9AALDH1A1 | |
| SCHEMBL537146 | 0.80 | LMNA (0.56) | LMNACTDSP1HSP90AA1KCNH2CA2 | |
| SCHEMBL536376 | 0.80 | LMNA (0.51) | LMNACTDSP1HSP90AA1KCNH2CA2 | |
| SCHEMBL9750265 | 0.79 | CA2 (0.41) | LMNACTDSP1HSP90AA1KCNH2CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4538164-A | LEUCO DYE, HYDROXYPHENOLIC ETHER DEVELOPER, OIL ABSORBING FILLER | RICOH CO., LTD. (JP) | 1985-08-27 | — | — | US | disclosed |