Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51052 | 0.98 | NR1H2 (0.46) | HSP90AA1KCNH2NR1H2CA2RAB9A | |
| SCHEMBL7756021 | 0.90 | HSP90AA1 (0.41) | HSP90AA1KCNH2NR1H2CA2RAB9A | |
| SCHEMBL51435 | 0.89 | CA2 (0.42) | HSP90AA1KCNH2NR1H2CA2RAB9A | |
| SCHEMBL9147326 | 0.88 | LMNA (0.46) | HSP90AA1KCNH2NR1H2CA2RAB9A | |
| SCHEMBL25738389 | 0.88 | CYP1A2 (0.43) | HSP90AA1KCNH2NR1H2CA2RAB9A | |
| SCHEMBL9750265 | 0.87 | CA2 (0.41) | HSP90AA1KCNH2NR1H2CA2RAB9A | |
| SCHEMBL16859777 | 0.87 | CA2 (0.41) | HSP90AA1KCNH2NR1H2CA2RAB9A | |
| SCHEMBL1835507 | 0.85 | LMNA (0.41) | HSP90AA1KCNH2NR1H2CA2RAB9A | |
| SCHEMBL8617352 | 0.85 | LTA4H (0.49) | NR1H2RAB9ALMNACTDSP1KDM4E | |
| SCHEMBL10935381 | 0.83 | ESR1 (0.54) | HSP90AA1KCNH2NR1H2CA2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2026-03-05 | — | — | US | disclosed |
| EP-3954745-B1 | REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME | KK PILOT CORPORATION ALSO TRADING AS PILOT CORPORATION (JP) | 2026-01-07 | — | — | EP | disclosed |
| US-12460099-B2 | Reversibly thermochromic composition, reversibly thermochromic microcapsule pigment encapsulating reversibly thermochromic composition, and writing instrument using reversibly thermochromic microcapsule pigment | THE PILOT INK CO., LTD. (JP) | 2025-11-04 | — | — | US | disclosed |
| US-12421411-B2 | Aqueous ink composition for reversibly thermochromic writing instrument, and refill and aqueous ballpoint pen incorporating aqueous ink composition for reversibly thermochromic writing instrument | KABUSHIKI KAISHA PILOT CORPORATION (JP) | 2025-09-23 | — | — | US | disclosed |
| CN-113646052-B | Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument | 百乐墨水株式会社 | 2024-05-17 | — | — | CN | disclosed |
| CN-113785023-B | Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same | 株式会社百乐 | 2023-05-12 | — | — | CN | disclosed |
| US-20230018132-A1 | REVERSIBLY THERMOCHROMIC AQUEOUS INKJET PRINTER INK COMPOSITION, INKJET PRINTER AND INK CARTRIDGE USING THE SAME | RISO TECHNOLOGIES CORPORATION (JP) | 2023-01-19 | — | — | US | disclosed |
| US-20220251406-A1 | AQUEOUS INK COMPOSITION FOR REVERSIBLY THERMOCHROMIC WRITING INSTRUMENT, AND REFILL AND AQUEOUS BALLPOINT PEN INCORPORATING AQUEOUS INK COMPOSITION FOR REVERSIBLY THERMOCHROMIC WRITING INSTRUMENT | KABUSHIKI KAISHA PILOT CORPORATION (ALSO TRADING AS PILOT CORPORATION) (JP) | 2022-08-11 | — | — | US | disclosed |
| US-20220169919-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | THE PILOT INK CO., LTD. (JP) | 2022-06-02 | — | — | US | disclosed |
| EP-3954745-A1 | REVERSIBLY THERMOCHROMIC AQUEOUS INK COMPOSITION FOR WRITING UTENSILS, AND REFILL AND WATER-BASED BALLPOINT PEN EACH INTERNALLY CONTAINING SAME | Kabushiki Kaisha Pilot Corporation (also trading as Pilot Corporation) (JP) | 2022-02-16 | — | — | EP | disclosed |
| EP-0403833-A2 | Recording material | NEW OJI PAPER CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |
| EP-0325231-A2 | Heat-sensitive recording material | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1989-07-26 | — | — | EP | disclosed |
| US-4835291-A | Divinyl compounds and chromogenic recording-material prepared by using thereof | YAMADA CHEMICAL CO., LTD. (JP) | 1989-05-30 | — | — | US | disclosed |
| EP-0307836-A2 | Heat-sensitive recording material | JUJO PAPER CO., LTD. (JP) | 1989-03-22 | — | — | EP | disclosed |
| US-4814320-A | DIVINYLPHTHALIDE DYE PRECURSOR MIXTURES, BINDER AND DEVELOPER; MOISTURE PROOF, OIL RESISTANCE | YAMADA CHEMICAL CO., LTD. (JP) | 1989-03-21 | — | — | US | disclosed |
| US-4808567-A | PHOTOSTABILITY, WATERPROOFING | YAMADA CHEMICAL CO., LTD. (JP) | 1989-02-28 | — | — | US | disclosed |
| US-4740494-A | SEPARATE LAYERS OF LEUCO DYE AND DEVELOPER | RICOH CO., LTD. (JP) | 1988-04-26 | — | — | US | disclosed |
| EP-0242169-A2 | Divinyl compounds and chromogenic recording material prepared by use thereof | YAMADA CHEMICAL CO., LTD. (JP) | 1987-10-21 | — | — | EP | disclosed |
| EP-0242170-A2 | Divinyl compounds and chromogenic recording-material prepared by use thereof | YAMADA CHEMICAL CO., LTD. (JP) | 1987-10-21 | — | — | EP | disclosed |
| US-4529993-A | Heat sensitive transfer medium | RICOH CO., LTD. (JP) | 1985-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260062580-A1 | REVERSIBLY THERMOCHROMIC COMPOSITION, REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING REVERSIBLY THERMOCHROMIC COMPOSITION, AND WRITING INSTRUMENT USING REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT | TYR, SCO2, HBB | HSP90AA1 1824/4885KCNH2 1089/4885NR1H2 2429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.