Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.47 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | JAK3 | P52333 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786522 | 0.83 | ALOX5 (0.55) | ALOX5GABRA2GABRB2L3MBTL1TRPM8 | |
| SCHEMBL9587212 | 0.74 | ALOX5 (0.52) | ALOX5GABRA2GABRB2L3MBTL1TRPM8 | |
| SCHEMBL1545025 | 0.74 | L3MBTL1 (0.53) | ALOX5GABRA2GABRB2L3MBTL1TRPM8 | |
| SCHEMBL18004078 | 0.72 | TARBP2 (0.62) | ALOX5GABRA2GABRB2L3MBTL1TRPM8 | |
| SCHEMBL18003298 | 0.72 | TARBP2 (0.50) | ALOX5GABRA2GABRB2L3MBTL1TRPM8 | |
| SCHEMBL9750620 | 0.71 | ALPL (0.44) | ALDH1A1MAPTKDM4EPOLB | |
| SCHEMBL4738316 | 0.71 | TARBP2 (0.48) | L3MBTL1TARBP2JAK2JAK3ALDH1A1 | |
| SCHEMBL421473 | 0.70 | ALOX5 (0.56) | ALOX5GABRA2GABRB2L3MBTL1TRPM8 | |
| SCHEMBL5775490 | 0.69 | ALOX5 (0.52) | ALOX5GABRA2GABRB2L3MBTL1TRPM8 | |
| SCHEMBL421079 | 0.69 | ALOX5 (0.55) | ALOX5GABRA2GABRB2L3MBTL1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5000775-A | 2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes | MONSANTO COMPANY (US) | 1991-03-19 | — | — | US | disclosed |