SCHEMBL9750679

SCHEMBL9750679

COc1cc(C(=O)N(C)CCN)cc(OC)c1OC

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 1/20 0.49
SCN2A Q99250 1/20 0.49
SCN3A Q9NY46 1/20 0.49
ALDH1A1 P00352 5/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
HTR2A P28223 1/20 0.45
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45
AOC3 Q16853 1/20 0.44
GAA P10253 1/20 0.43
TUBB4A P04350 2/20 0.43
TUBB P07437 2/20 0.43
TUBA3C P0DPH7 2/20 0.43
TUBA1B P68363 2/20 0.43
TUBA4A P68366 2/20 0.43
TUBB4B P68371 2/20 0.43
TUBB3 Q13509 2/20 0.43
TUBB2A Q13885 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9750696 0.83 SCN1A (0.48) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL7276036 0.82 KMT2A (0.49) SCN1ASCN2ASCN3AALDH1A1MEN1
Hydrochloric Acid SCHEMBL9750666 0.81 KMT2A (0.48) SCN1ASCN2ASCN3AALDH1A1MEN1
Hydrochloric Acid SCHEMBL7266825 0.81 KMT2A (0.48) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL9545203 0.79 HSP90AA1 (0.61) SCN1ASCN2ASCN3AALDH1A1MEN1
Acetone SCHEMBL9750671 0.79 KMT2A (0.46) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL10789209 0.78 ALDH1A1 (0.57) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL7376402 0.78 TUBB4A (0.51) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL13286764 0.77 PKM (0.56) SCN1ASCN2ASCN3AALDH1A1MEN1
SCHEMBL6507928 0.76 ALDH1A1 (0.58) SCN1ASCN2ASCN3AALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4988735-A Ethylene diamine active cardiovascular therapy SIMES (IT) 1991-01-29 US disclosed