Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 3/20 | 0.58 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750938 | 0.86 | HMGCR (0.51) | HMGCRKMT2AFAAHCNR1CNR2 | |
| SCHEMBL9750803 | 0.82 | HMGCR (0.49) | HMGCRTGFBR1HSP90AA1HSP90AB1GLA | |
| SCHEMBL9521499 | 0.81 | HMGCR (0.62) | HMGCRGLAPOLB | |
| SCHEMBL9518373 | 0.80 | HMGCR (0.58) | HMGCRGLAPOLB | |
| SCHEMBL9518298 | 0.76 | HMGCR (0.59) | HMGCRGLAPOLB | |
| SCHEMBL9518290 | 0.76 | HMGCR (0.59) | HMGCRGLAPOLB | |
| SCHEMBL9751010 | 0.76 | HMGCR (0.49) | HMGCRTGFBR1KMT2A | |
| SCHEMBL10455380 | 0.75 | HMGCR (0.45) | HMGCR | |
| SCHEMBL9750923 | 0.74 | HMGCR (1.00) | HMGCR | |
| SCHEMBL9518598 | 0.73 | HMGCR (0.56) | HMGCRTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |