Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 6/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750818 | 0.88 | HMGCR (0.59) | HMGCRPOLBALDH1A1MAPTABCB1 | |
| SCHEMBL9518353 | 0.88 | HMGCR (0.59) | HMGCRPOLBALDH1A1MAPTABCB1 | |
| SCHEMBL8846389 | 0.87 | HMGCR (0.55) | HMGCRALDH1A1MAPTABCB1KDM4E | |
| SCHEMBL9750954 | 0.82 | HMGCR (0.57) | HMGCRPOLBALDH1A1MAPTABCB1 | |
| SCHEMBL9750852 | 0.80 | HMGCR (0.53) | HMGCRALDH1A1MAPTABCB1KDM4E | |
| SCHEMBL9024748 | 0.79 | ELAVL1 (0.45) | HMGCRL3MBTL1PTGS2 | |
| SCHEMBL9751046 | 0.78 | HMGCR (0.55) | HMGCRALDH1A1PTGS2 | |
| SCHEMBL9518442 | 0.77 | HMGCR (0.51) | HMGCRALDH1A1MAPTABCB1KDM4E | |
| SCHEMBL9518920 | 0.74 | HMGCR (0.67) | HMGCR | |
| SCHEMBL9750972 | 0.74 | HMGCR (1.00) | HMGCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |