Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.34 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.34 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750926 | 0.86 | HMGCR (0.54) | HMGCRADORA2AADORA1ABCB1PTGS2 | |
| SCHEMBL9518535 | 0.86 | HMGCR (0.54) | HMGCRADORA2AADORA1ABCB1PTGS2 | |
| SCHEMBL9751046 | 0.84 | HMGCR (0.55) | HMGCRALDH1A1ADORA2AADORA1PTGS2 | |
| SCHEMBL9521360 | 0.74 | HMGCR (0.57) | HMGCRPTGDR2 | |
| SCHEMBL9750954 | 0.74 | HMGCR (0.57) | HMGCRALDH1A1ABCB1LMNAPTGS2 | |
| SCHEMBL9518437 | 0.73 | HMGCR (0.56) | HMGCRADORA2AADORA1PTGS2PTGS1 | |
| SCHEMBL9750945 | 0.73 | HMGCR (0.56) | HMGCRADORA2AADORA1PTGS2PTGS1 | |
| SCHEMBL9750882 | 0.73 | HMGCR (1.00) | HMGCR | |
| SCHEMBL10505092 | 0.73 | HMGCR (0.52) | HMGCRABCB1 | |
| SCHEMBL9518755 | 0.71 | SLC6A4 (0.47) | HMGCRALDH1A1ABCB1LMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |