Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 8/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518437 | 1.00 | HMGCR (0.56) | HMGCRADORA2AADORA1PTGS2PTGS1 | |
| SCHEMBL9751046 | 0.86 | HMGCR (0.55) | HMGCRADORA2AADORA1PTGS2PTGS1 | |
| SCHEMBL9750926 | 0.85 | HMGCR (0.54) | HMGCRADORA2AADORA1PTGS2MET | |
| SCHEMBL9518535 | 0.85 | HMGCR (0.54) | HMGCRADORA2AADORA1PTGS2MET | |
| SCHEMBL9518155 | 0.82 | HMGCR (0.53) | HMGCRADORA2AADORA1MAPK13MAPK12 | |
| SCHEMBL9750818 | 0.80 | HMGCR (0.59) | HMGCRPTGS2 | |
| SCHEMBL9518353 | 0.80 | HMGCR (0.59) | HMGCRPTGS2 | |
| SCHEMBL10397745 | 0.78 | HMGCR (0.38) | HMGCRADORA2AADORA1PTGS2PTGS1 | |
| SCHEMBL10397744 | 0.78 | HMGCR (0.38) | HMGCRADORA2AADORA1PTGS2PTGS1 | |
| SCHEMBL9518298 | 0.78 | HMGCR (0.59) | HMGCRPTGS2PTGS1MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |