Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HMGCR | P04035 | 5/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9750808 | 0.87 | HMGCR (0.51) | KDM4EALDH1A1L3MBTL1TDP1HMGCR | |
| SCHEMBL9518614 | 0.80 | HMGCR (0.48) | KDM4EALDH1A1L3MBTL1TDP1HMGCR | |
| SCHEMBL9518289 | 0.80 | HMGCR (0.47) | KDM4EALDH1A1L3MBTL1TDP1HMGCR | |
| SCHEMBL9750899 | 0.76 | HMGCR (0.46) | KDM4EALDH1A1L3MBTL1TDP1HMGCR | |
| SCHEMBL9750902 | 0.76 | HMGCR (0.46) | KDM4EALDH1A1L3MBTL1TDP1HMGCR | |
| SCHEMBL9655512 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1TDP1HMGCR | |
| SCHEMBL9695120 | 0.74 | KDM4E (0.46) | KDM4EALDH1A1L3MBTL1TDP1HMGCR | |
| SCHEMBL9750852 | 0.74 | HMGCR (0.53) | KDM4EALDH1A1L3MBTL1TDP1HMGCR | |
| SCHEMBL9750820 | 0.73 | AR (0.71) | KDM4EALDH1A1HMGCRARGAA | |
| SCHEMBL9441634 | 0.72 | MEN1 (0.56) | KDM4EALDH1A1L3MBTL1TDP1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5055484-A | Anticholesterol and antilipemic agent | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-08 | — | — | US | disclosed |