Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.31 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.30 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.30 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.30 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.30 |
| ▸ | GRM8 | O00222 | 1/20 | 0.30 |
| ▸ | GRM6 | O15303 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL10379722 | 1.00 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL9750989 | 0.97 | ALOX15 (0.38) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL27806428 | 0.97 | ALOX15 (0.38) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL28378561 | 0.93 | GSR (0.37) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL21768802 | 0.93 | GSR (0.37) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL10379721 | 0.93 | ALOX15 (0.36) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL9751058 | 0.93 | ALOX15 (0.41) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL27730526 | 0.92 | BLM (0.47) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL9750983 | 0.92 | ALOX15 (0.34) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL21774926 | 0.91 | SLC7A5 (0.46) | SLC7A5SLC1A3SLC1A2CYP3A4SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347435-A4 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | — | 1991-11-21 | — | — | EP | claimed |
| EP-0347435-A1 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | BIOGEN, INC. (US) | 1989-12-27 | — | — | EP | claimed |
| WO-1989001940-A1 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | BIOGEN, INC. (US) | 1989-03-09 | — | — | WO | claimed |
| EP-0347435-A4 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | — | 1991-11-21 | — | — | EP | disclosed |
| EP-0347435-A1 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | BIOGEN, INC. (US) | 1989-12-27 | — | — | EP | disclosed |
| WO-1989001940-A1 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | BIOGEN, INC. (US) | 1989-03-09 | — | — | WO | disclosed |