Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL10379721 | 0.96 | ALOX15 (0.36) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL9750900 | 0.94 | ALOX15 (0.34) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL9750989 | 0.94 | ALOX15 (0.38) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL9750903 | 0.92 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL10379722 | 0.92 | ALOX15 (0.40) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL9751058 | 0.91 | ALOX15 (0.41) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL27806428 | 0.89 | ALOX15 (0.38) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL21768802 | 0.85 | GSR (0.37) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL28378561 | 0.85 | GSR (0.37) | ALOX15BLMPMP22KMT2ASLC7A5 | |
| Histidine SCHEMBL17628714 | 0.84 | BLM (0.47) | ALOX15BLMPMP22KMT2ASLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347435-A4 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | — | 1991-11-21 | — | — | EP | claimed |
| WO-1990004414-A1 | CONJUGATES OF SOLUBLE T4 PROTEINS AND TOXINS AND METHODS FOR TREATING OR PREVENTING AIDS, ARC AND HIV INFECTION | BIOGEN, INC. (US) | 1990-05-03 | — | — | WO | claimed |
| EP-0347435-A1 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | BIOGEN, INC. (US) | 1989-12-27 | — | — | EP | claimed |
| WO-1989001940-A1 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | BIOGEN, INC. (US) | 1989-03-09 | — | — | WO | claimed |
| EP-0347435-A4 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | — | 1991-11-21 | — | — | EP | disclosed |
| EP-0378643-A4 | COMBINATIONS OF SOLUBLE T4 PROTEINS AND ANTI-RETROVIRAL AGENTS AND METHODS FOR TREATING OR PREVENTING AIDS, ARC AND HIV INFECTION | — | 1990-12-27 | — | — | EP | disclosed |
| EP-0378643-A1 | COMBINATIONS OF SOLUBLE T4 PROTEINS AND ANTI-RETROVIRAL AGENTS AND METHODS FOR TREATING OR PREVENTING AIDS, ARC AND HIV INFECTION | BIOGEN, INC. (US) | 1990-07-25 | — | — | EP | disclosed |
| WO-1990004414-A1 | CONJUGATES OF SOLUBLE T4 PROTEINS AND TOXINS AND METHODS FOR TREATING OR PREVENTING AIDS, ARC AND HIV INFECTION | BIOGEN, INC. (US) | 1990-05-03 | — | — | WO | disclosed |
| EP-0347435-A1 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | BIOGEN, INC. (US) | 1989-12-27 | — | — | EP | disclosed |
| WO-1989011860-A1 | COMBINATIONS OF SOLUBLE T4 PROTEINS AND ANTI-RETROVIRAL AGENTS AND METHODS FOR TREATING OR PREVENTING AIDS, ARC AND HIV INFECTION | BIOGEN, INC. (US) | 1989-12-14 | — | — | WO | disclosed |
| WO-1989001940-A1 | DNA SEQUENCES, RECOMBINANT DNA MOLECULES AND PROCESSES FOR PRODUCING SOLUBLE T4 PROTEINS | BIOGEN, INC. (US) | 1989-03-09 | — | — | WO | disclosed |