Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.70 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.68 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 4/20 | 0.62 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | TYK2 | P29597 | 1/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8299753 | 0.89 | TDP1 (0.68) | HTTSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL29777389 | 0.88 | SMN1; SMN2 (0.68) | KDRPABPC1EIF4HHTTSMN1; SMN2 | |
| SCHEMBL975125 | 0.88 | SMN1; SMN2 (0.68) | KDRPABPC1EIF4HHTTSMN1; SMN2 | |
| SCHEMBL29777391 | 0.88 | SMN1; SMN2 (0.68) | KDRPABPC1EIF4HHTTSMN1; SMN2 | |
| SCHEMBL11264182 | 0.86 | SMN1; SMN2 (0.60) | KDRHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9868437 | 0.85 | KDM4E (0.59) | HTTSMN1; SMN2NPC1RAB9AGRM4 | |
| SCHEMBL5503426 | 0.85 | NPC1 (0.58) | KDRHTTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10352137 | 0.84 | METAP2 (0.60) | KDRPABPC1EIF4HHTTSMN1; SMN2 | |
| SCHEMBL8341671 | 0.83 | POLB (0.63) | HTTSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL29510019 | 0.82 | KDR (1.00) | KDRPABPC1EIF4HSMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5077408-A | PROCESS FOR THE SYNTHESIS OF OXAZOLOPYRIDINE COMPOUNDS | SCIENCE ET ORGANISATION (FR) | 1991-12-31 | — | — | US | disclosed |