SCHEMBL9751366

SCHEMBL9751366

CCN(CC)CCN1SCCC1=O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.57
MGLL Q99685 1/20 0.57
ACHE P22303 3/20 0.38
HTR1A P08908 1/20 0.33
MPO P05164 1/20 0.33
PDE4B Q07343 1/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A2 P23975 1/20 0.32
HRH1 P35367 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPK1 P28482 1/20 0.32
CYP2C19 P33261 1/20 0.32
HSD17B10 Q99714 1/20 0.32
DRD2 P14416 1/20 0.31
DRD3 P35462 1/20 0.31
KCNH2 Q12809 1/20 0.31
TOP2A P11388 1/20 0.31
POLB P06746 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6277309 0.76 FAAH (0.86) FAAHMGLLDRD2DRD3MAPT
SCHEMBL7927918 0.73 MGLL (1.00) FAAHMGLLCYP1A2CYP3A4CYP2D6
SCHEMBL7926717 0.73 MGLL (1.00) FAAHMGLLCYP1A2CYP3A4CYP2D6
SCHEMBL9751393 0.73 MGLL (1.00) FAAHMGLLCYP1A2CYP3A4CYP2D6
SCHEMBL6536728 0.66
SCHEMBL7290587 0.66 PIK3CD (0.47) ACHECYP1A2CYP2D6MAPK1CYP2C19
SCHEMBL9822376 0.64 ACHE (0.44) ACHEPDE4BCYP1A2CYP2D6CYP2C19
SCHEMBL11054712 0.64 ACHE (0.47) FAAHMGLLACHESLC6A4SLC6A2
SCHEMBL6948445 0.64 SIGMAR1 (0.38) ACHEMPOSLC6A4SLC6A2DRD2
SCHEMBL7289876 0.63 ACHE (0.37) ACHEHTR1APDE4BDRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5008150-A Hydrophilic colloid, amine salt or quarternary ammonium, ester of p-hydroxybenzoic acid; improved adhesion MITSUBISHI PAPER MILLS LIMITED (JP) 1991-04-16 US disclosed