Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.37 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.37 |
| ▸ | ABAT | P80404 | 1/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27685352 | 0.80 | MAPT (0.55) | ALDH1A1CYP3A4MAPTLMNATDP1 | |
| SCHEMBL4220780 | 0.77 | TSHR (0.47) | ALDH1A1CYP3A4MAPTLMNATDP1 | |
| SCHEMBL3691338 | 0.74 | CYP19A1 (0.50) | ALDH1A1CYP3A4MAPTLMNATSHR | |
| SCHEMBL7528440 | 0.73 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MAPTLMNATDP1 | |
| SCHEMBL6754385 | 0.73 | LMNA (0.54) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL7530821 | 0.73 | VCAM1 (0.62) | MAPTLMNAMEN1KMT2APOLB | |
| SCHEMBL5080205 | 0.72 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPTCTSBLMNA | |
| SCHEMBL801576 | 0.70 | VCAM1 (0.39) | ALDH1A1MAPTLMNATSHRMEN1 | |
| SCHEMBL266593 | 0.70 | ALDH1A1 (0.76) | ALDH1A1CYP3A4MAPTLMNATDP1 | |
| SCHEMBL221077 | 0.70 | ALDH1A1 (0.57) | ALDH1A1CYP3A4MAPTCTSBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109761944-A | A kind of chrysin amide derivatives and preparation method thereof and medical usage | 武汉翼博济生生物科技有限公司 | 2019-05-17 | — | — | CN | claimed |
| EP-0406334-A4 | HYDROGEL DYE FILM SENSING ELEMENTS AND THEIR PREPARATION | — | 1991-11-13 | — | — | EP | disclosed |
| EP-0406334-A1 | HYDROGEL DYE FILM SENSING ELEMENTS AND THEIR PREPARATION | NELLCOR INCORPORATED (US) | 1991-01-09 | — | — | EP | disclosed |
| WO-1990000572-A1 | HYDROGEL DYE FILM SENSING ELEMENTS AND THEIR PREPARATION | NELLCOR INCORPORATED (US) | 1990-01-25 | — | — | WO | disclosed |