Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10648237 | 0.78 | CRHBP (0.52) | CRHBPCRHR2KEAP1NFE2L2MEN1 | |
| SCHEMBL10645862 | 0.76 | CRHBP (0.50) | CRHBPCRHR2KEAP1NFE2L2MEN1 | |
| SCHEMBL10490096 | 0.76 | PABPC1 (0.50) | CRHBPCRHR2KEAP1NFE2L2MEN1 | |
| SCHEMBL10795218 | 0.76 | CYP1A2 (0.43) | PAX8MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL9404195 | 0.76 | PARP1 (0.43) | PAX8MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7292431 | 0.75 | PAX8 (0.39) | ELANEPAX8CTSGMEN1KMT2A | |
| SCHEMBL7300968 | 0.74 | CDK5 (0.50) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL18751635 | 0.73 | CRHBP (0.47) | CRHBPCRHR2KEAP1NFE2L2KMT2A | |
| SCHEMBL325965 | 0.73 | MEN1 (0.51) | MEN1KMT2AALDH1A1HPGDTSHR | |
| SCHEMBL27917251 | 0.73 | KEAP1 (0.47) | CRHBPCRHR2KEAP1NFE2L2ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0400066-A4 | HEAT-TRANSFER FLUIDS AND PROCESS FOR PREPARING THE SAME | — | 1991-03-20 | — | — | EP | disclosed |
| EP-0400066-A1 | HEAT-TRANSFER FLUIDS AND PROCESS FOR PREPARING THE SAME | THE DOW CHEMICAL COMPANY (US) | 1990-12-05 | — | — | EP | disclosed |
| WO-1989007634-A1 | HEAT-TRANSFER FLUIDS AND PROCESS FOR PREPARING THE SAME | THE DOW CHEMICAL COMPANY (US) | 1989-08-24 | — | — | WO | disclosed |