Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.40 |
| ▸ | ACACA | Q13085 | 3/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969875 | 0.82 | MAPT (0.46) | ACACBCYP19A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL12204789 | 0.78 | MAPT (0.41) | ACACBMAPTSMN1; SMN2FFAR1 | |
| SCHEMBL12204752 | 0.77 | ACACB (0.39) | ACACBCYP19A1MAPTFFAR1PIK3CD | |
| SCHEMBL20784571 | 0.77 | MAPT (0.49) | ACACBCYP19A1MAPTSMN1; SMN2RAB9A | |
| SCHEMBL8968866 | 0.76 | ACACB (0.62) | ACACB | |
| SCHEMBL10459939 | 0.75 | ACACB (0.41) | ACACBACACAMAPTSMN1; SMN2RAB9A | |
| SCHEMBL9621041 | 0.74 | LPL (0.46) | ACACBACACAHTTSMN1; SMN2L3MBTL1 | |
| SCHEMBL12230280 | 0.74 | ACACB (0.47) | ACACBCYP19A1MAPT | |
| SCHEMBL12204799 | 0.74 | HPGD (0.48) | ACACBMAPTSMN1; SMN2FFAR1 | |
| SCHEMBL8969725 | 0.74 | MAPT (0.54) | CYP19A1MAPTSMN1; SMN2RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445257-A1 | PYRIDINE DERIVATIVES AND A LIQUID CRYSTAL MEDIUM. | MERCK PATENT GMBH (DE) | 1991-09-11 | — | — | EP | disclosed |