Butopyronoxyl

Butopyronoxyl

SCHEMBL9751913

CCCCOC(=O)C1=CC(=O)CC(C)(C)O1.CCCCc1cccc2c1C(O)(C(=O)O)c1ccccc1-2

nearest known ligand 0.36

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 2/20 0.36
MAPT P10636 2/20 0.36
ALDH1A1 P00352 2/20 0.36
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 3/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
TSHR P16473 3/20 0.33
THRB P10828 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.32
CHRM2 P08172 2/20 0.32
CHRM1 P11229 2/20 0.32
CHRM3 P20309 2/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
POLB P06746 1/20 0.32
KDM4E B2RXH2 1/20 0.32
APAF1 O14727 1/20 0.32
NSD2 O96028 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butopyronoxyl SCHEMBL8952222 0.78 TSHR (0.40) ALDH1A1CYP2C9CYP2C19TDP1L3MBTL1
Butopyronoxyl SCHEMBL121985 0.78 TSHR (0.42) ALDH1A1CYP2C9CYP2C19TDP1L3MBTL1
SCHEMBL1879231 0.78 THRB (0.54) TDP1THRBCHRM2CHRM1CHRM3
Butopyronoxyl SCHEMBL2374236 0.77 TSHR (0.39) ALDH1A1CYP2C9CYP2C19TDP1L3MBTL1
Butopyronoxyl SCHEMBL7635420 0.75 TSHR (0.49) ALDH1A1CYP2C19TDP1L3MBTL1TSHR
SCHEMBL9706981 0.64 TSHR (0.50) TDP2MAPTALDH1A1CYP2C9CYP2C19
SCHEMBL145937 0.64 TSHR (0.50) TDP2MAPTALDH1A1CYP2C9CYP2C19
SCHEMBL11304697 0.63 HCAR2 (0.60) ALDH1A1TDP1L3MBTL1TSHRCYP3A4
SCHEMBL17942873 0.63 TSHR (0.49) TDP2MAPTALDH1A1CYP2C9CYP2C19
SCHEMBL27778147 0.61 NR1H2 (0.38) CYP2C9CHRM2CHRM1CHRM3ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0449975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS. BATTELLE MEMORIAL INSTITUTE (US) 1991-10-09 EP claimed
EP-0449975-A1 NON-TIN-BASED, LOW TOXICITY ANTI-FOULING AGENTS. BATTELLE MEMORIAL INSTITUTE (US) 1991-10-09 EP disclosed