SCHEMBL9752018

SCHEMBL9752018

CCS(=O)(=O)c1ccc(C(=O)O)c([N+](=O)[O-])c1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TSHR P16473 1/20 0.44
SLC25A1 P53007 1/20 0.43
DTYMK P23919 1/20 0.43
RXRA P19793 1/20 0.43
POLB P06746 2/20 0.42
FLT1 P17948 1/20 0.42
FLT4 P35916 1/20 0.42
KDR P35968 1/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
VCAM1 P19320 3/20 0.41
HCAR3 P49019 2/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1202449 0.84 ALDH1A1 (0.56) HTTALDH1A1TSHRSLC25A1DTYMK
Hydrogen Peroxide SCHEMBL28991385 0.84 ALDH1A1 (0.56) HTTALDH1A1TSHRSLC25A1DTYMK
SCHEMBL28435633 0.83 ALDH1A1 (0.55) HTTALDH1A1TSHRSLC25A1DTYMK
Hydrochloric Acid SCHEMBL9617579 0.83 ALDH1A1 (0.55) HTTALDH1A1TSHRSLC25A1DTYMK
SCHEMBL1533651 0.82 ALDH1A1 (0.54) ALDH1A1TSHRSLC25A1DTYMKPOLB
Propylamine SCHEMBL18093556 0.81 ALDH1A1 (0.48) HTTALDH1A1TSHRSLC25A1POLB
SCHEMBL18093521 0.81 ALDH1A1 (0.48) HTTALDH1A1TSHRVCAM1HCAR3
SCHEMBL29787232 0.81 CA2 (0.65) ALDH1A1POLBCA12CA1CA2
SCHEMBL9795946 0.81 CA2 (0.65) ALDH1A1POLBCA12CA1CA2
SCHEMBL9795938 0.80 VCAM1 (0.66) HTTALDH1A1SMN1; SMN2CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104059001-B A kind of adjacent benzoic preparation method of nitro sulfuryl 华中师范大学 2016-06-08 CN disclosed
EP-0447421-A1 PREPARATION OF 2-(CHLORO, BROMO OR NITRO)-4-(ALKYLSULFONYL)BENZOIC ACIDS AND INTERMEDIATES. ICI AMERICA INC (US) 1991-09-25 EP disclosed