Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | MC5R | P33032 | 5/20 | 0.52 |
| ▸ | MC3R | P41968 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | MC4R | P32245 | 3/20 | 0.50 |
| ▸ | NMBR | P28336 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | MC1R | Q01726 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24588379 | 0.91 | ALDH1A1 (0.58) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL3344871 | 0.89 | MC4R (0.55) | MC5RMC3RMC4RMC1R | |
| SCHEMBL7271569 | 0.89 | MC4R (0.55) | MC5RMC3RMC4RMC1R | |
| SCHEMBL24500027 | 0.85 | GHSR (0.69) | — | |
| SCHEMBL5500900 | 0.83 | PPARG (0.63) | KMT2AMEN1HCRTR1PPARG | |
| SCHEMBL19051488 | 0.83 | PPARG (0.66) | KMT2AMEN1HCRTR1PPARG | |
| SCHEMBL28359802 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL28359800 | 0.83 | ALDH1A1 (0.61) | ALDH1A1MAPTGAAKDM4EL3MBTL1 | |
| SCHEMBL29511241 | 0.83 | BMP1 (0.53) | MAPTKDM4EKMT2AMEN1MC4R | |
| Hydrochloric Acid SCHEMBL6287925 | 0.83 | HDAC1 (0.51) | ALDH1A1MAPTGAAKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0449884-A4 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | — | 1991-10-30 | — | — | EP | disclosed |
| EP-0449884-A1 | DERIVATIVES OF TETRAPEPTIDES AS CCK AGONISTS | ABBOTT LABORATORIES (US) | 1991-10-09 | — | — | EP | disclosed |