Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752488 | 0.74 | MAPT (0.37) | HTTATML3MBTL1MAPK1MAPT | |
| SCHEMBL9872195 | 0.67 | SMN1; SMN2 (0.42) | HTTL3MBTL1MAPK1MAPTPOLB | |
| SCHEMBL8579452 | 0.66 | ATM (0.39) | ATMPOLBKDM4ERAB9ASMN1; SMN2 | |
| SCHEMBL9752708 | 0.66 | PDE4B (0.44) | RAB9A | |
| Hydrochloric Acid SCHEMBL9752508 | 0.65 | PDE4B (0.43) | RAB9A | |
| SCHEMBL9752596 | 0.64 | PDE4B (0.39) | L3MBTL1POLBRAB9A | |
| SCHEMBL9879251 | 0.64 | PDE4B (0.42) | L3MBTL1POLBRAB9A | |
| SCHEMBL9752552 | 0.63 | ALDH1A1 (0.37) | HTTATML3MBTL1MAPK1MAPT | |
| SCHEMBL9870800 | 0.63 | PDE4B (0.45) | MAPK1KDM4EALDH1A1 | |
| SCHEMBL9752624 | 0.63 | PDE4B (0.45) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010664-A1 | PYRIDAZINO[4,5-b]INDOLIZINES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-07-25 | — | — | WO | disclosed |