Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27602871 | 0.90 | POLB (0.50) | POLBNPSR1MAPTL3MBTL1TSHR | |
| SCHEMBL28003319 | 0.86 | POLB (0.69) | POLBNPSR1LMNAMAP3K14 | |
| SCHEMBL28003324 | 0.86 | POLB (0.55) | POLBNPSR1MAPTMAPK1LMNA | |
| SCHEMBL17457962 | 0.83 | HTT (0.54) | POLBNPSR1MAPT | |
| SCHEMBL9752787 | 0.82 | POLB (0.63) | POLBNPSR1MAPTL3MBTL1 | |
| SCHEMBL15331455 | 0.82 | POLB (0.46) | POLBNPSR1MAPTTSHRPSMB1 | |
| SCHEMBL18764514 | 0.82 | ALDH1A1 (0.61) | POLBNPSR1L3MBTL1TSHRLMNA | |
| SCHEMBL11540601 | 0.80 | HTR7 (0.45) | POLBNPSR1 | |
| SCHEMBL31310034 | 0.80 | KLKB1 (0.51) | POLBNPSR1MAPTTSHRPSMB1 | |
| SCHEMBL1768170 | 0.80 | POLB (0.61) | POLBNPSR1MAPTL3MBTL1PSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | claimed |