Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 6/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008297 | 0.92 | SLC28A3 (0.47) | SLC28A3NPC1HPGDMAPK1HTT | |
| SCHEMBL8658359 | 0.87 | SLC28A3 (0.44) | SLC28A3NPC1HPGDMAPK1HTT | |
| SCHEMBL9752751 | 0.83 | GPR84 (0.40) | SLC28A3NPC1HPGDMAPK1HTT | |
| SCHEMBL9437050 | 0.81 | NPC1 (0.56) | SLC28A3NPC1HPGDMAPK1HTT | |
| SCHEMBL110236 | 0.79 | SLC28A3 (0.71) | SLC28A3NPC1HPGDMAPK1HTT | |
| SCHEMBL11574798 | 0.79 | AKT1 (0.40) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL28032554 | 0.79 | NPC1 (0.58) | SLC28A3NPC1HPGDMAPK1HTT | |
| SCHEMBL70160 | 0.77 | PTGS2 (0.57) | GPR84GRIN2DGRIN2AGRIN2BGRIN2C | |
| SCHEMBL24756199 | 0.76 | LMNA (0.43) | SLC28A3NPC1HPGDMAPK1HTT | |
| SCHEMBL9743295 | 0.76 | HTT (0.72) | SLC28A3NPC1HPGDMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009595-A1 | ANTI-VIRAL COMPOSITIONS | SMITHKLINE BEECHAM CORPORATION (US) | 1991-07-11 | — | — | WO | disclosed |