SCHEMBL975276

SCHEMBL975276

CC(=O)c1ccc2c(CBr)c3ccccc3c(CBr)c2c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.53
HPGD P15428 3/20 0.53
MAPT P10636 3/20 0.53
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
PKM P14618 1/20 0.42
S100A4 P26447 1/20 0.41
LMNA P02545 1/20 0.41
KMT2A Q03164 4/20 0.40
MEN1 O00255 3/20 0.40
APAF1 O14727 1/20 0.40
KDM4E B2RXH2 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
SLC2A1 P11166 1/20 0.40
KIF11 P52732 1/20 0.40
POLB P06746 1/20 0.37
HTR1A P08908 1/20 0.37
HTR1D P28221 1/20 0.37
HTR1B P28222 1/20 0.37
CES2 O00748 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20313050 0.87 MAPT (0.39) ALDH1A1HPGDMAPTNPC1RAB9A
SCHEMBL20313049 0.84 KDM4E (0.46) ALDH1A1HPGDKDM4ECES2CES1
SCHEMBL974529 0.82 KIF11 (0.54) ALDH1A1HPGDMAPTNPC1RAB9A
SCHEMBL10023267 0.79 ALDH1A1 (0.66) ALDH1A1HPGDMAPTNPC1RAB9A
SCHEMBL1042811 0.78 PLK1 (0.40) ALDH1A1MAPTLMNAKMT2AMEN1
SCHEMBL29780395 0.74 ALDH1A1 (0.59) ALDH1A1HPGDMAPTNPC1RAB9A
SCHEMBL975343 0.74 ALDH1A1 (0.59) ALDH1A1HPGDMAPTNPC1RAB9A
SCHEMBL975345 0.72 ALDH1A1 (0.53) ALDH1A1HPGDMAPTNPC1RAB9A
SCHEMBL975344 0.72 ALDH1A1 (0.53) ALDH1A1HPGDMAPTNPC1RAB9A
SCHEMBL1719724 0.72 ALDH1A1 (0.45) ALDH1A1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023085617-A1 STRUCTURE COMPRISING ANTHRACENEDIBORONIC ACID-BASED COMPOUND FOR DETECTING GLUCOSE, PREPARATION METHOD THEREFOR, AND USE THEREOF 재단법인 대구경북첨단의료산업진흥재단 2023-05-19 WO disclosed
US-8822722-B2 Fluorescent hydrogel and method for producing the same, and sensor for measuring saccharides using the same TERUMO KABUSHIKI KAISHA (JP) 2014-09-02 US disclosed
US-8822722-B2 Fluorescent hydrogel and method for producing the same, and sensor for measuring saccharides using the same TERUMO KABUSHIKI KAISHA (JP) 2014-09-02 US disclosed
US-20130267800-A1 FLUORESCENT HYDROGEL AND METHOD FOR PRODUCING THE SAME, AND SENSOR FOR MEASURING SACCHARIDES USING THE SAME THE UNIVERSITY OF TOKYO (JP) 2013-10-10 US disclosed
US-20130267800-A1 FLUORESCENT HYDROGEL AND METHOD FOR PRODUCING THE SAME, AND SENSOR FOR MEASURING SACCHARIDES USING THE SAME THE UNIVERSITY OF TOKYO (JP) 2013-10-10 US disclosed
US-20130267800-A1 FLUORESCENT HYDROGEL AND METHOD FOR PRODUCING THE SAME, AND SENSOR FOR MEASURING SACCHARIDES USING THE SAME THE UNIVERSITY OF TOKYO (JP) 2013-10-10 US disclosed
US-7873398-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2011-01-18 US disclosed
US-7524985-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2009-04-28 US disclosed
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-12-25 US disclosed
US-7388110-B2 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-06-17 US disclosed
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2008-01-24 US disclosed
EP-1619229-B1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO CORP (JP) 2007-04-11 EP disclosed
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA 2006-01-26 US disclosed
EP-1619229-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor TERUMO KABUSHIKI KAISHA (JP) 2006-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080319288-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 ALDH1A1 167/4885HPGD 442/4885MAPT 4815/4885
US-20060020182-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 ALDH1A1 273/4885HPGD 632/4885MAPT 4783/4885
US-20080021236-A1 Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor ACMSD, QPCT, B3GNT2 ALDH1A1 273/4885HPGD 632/4885MAPT 4783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.