Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31146421 | 0.82 | THRB (0.52) | THRBCA12CA9TP53HSD17B10 | |
| SCHEMBL181822 | 0.82 | THRB (0.52) | THRBCA12CA9TP53HSD17B10 | |
| SCHEMBL1042050 | 0.78 | ALDH1A1 (0.48) | SRCALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL975276 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNASMN1; SMN2POLB | |
| SCHEMBL29791960 | 0.78 | ALDH1A1 (0.45) | PLK1HSD17B10ALDH1A1TSHRPTPN1 | |
| SCHEMBL1719724 | 0.78 | ALDH1A1 (0.45) | PLK1HSD17B10ALDH1A1TSHRPTPN1 | |
| SCHEMBL1666371 | 0.75 | THRB (0.50) | THRBCA12CA9TP53HSD17B10 | |
| SCHEMBL1040657 | 0.74 | HSD17B10 (0.47) | THRBCA12CA9TP53HSD17B10 | |
| SCHEMBL12527459 | 0.72 | CYP3A4 (0.46) | PLK1TP53HSD17B10ALDH1A1KDM4E | |
| SCHEMBL8902531 | 0.71 | MAPT (0.50) | EGFRALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2270114-B1 | PHOTOBASE GENERATOR | SAN APRO LTD (JP) | 2014-07-09 | — | — | EP | disclosed |
| US-8329771-B2 | Photobase generator | SAN-APRO LIMITED (JP) | 2012-12-11 | — | — | US | disclosed |
| US-20110028585-A1 | PHOTOBASE GENERATOR | SAN-APRO LIMITED (JP) | 2011-02-03 | — | — | US | disclosed |
| EP-2270114-A1 | PHOTOBASE GENERATOR | San-Apro Limited (JP) | 2011-01-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028585-A1 | PHOTOBASE GENERATOR | CCKBR, XDH, PPOX | PLK1 2561/4885THRB 2649/4885CA12 1659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.