Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 5/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7250898 | 0.79 | PPARA (0.57) | CTSKCTSBCTSSGABRB1GABRB2 | |
| SCHEMBL7289392 | 0.79 | PPARA (0.57) | CTSKCTSBCTSSGABRB1GABRB2 | |
| SCHEMBL5228193 | 0.79 | PPARA (0.57) | CTSKCTSBCTSSGABRB1GABRB2 | |
| SCHEMBL9331930 | 0.78 | CTSS (0.69) | CTSKCTSBCTSSRENHDAC8 | |
| SCHEMBL8740509 | 0.78 | CTSS (0.69) | CTSKCTSBCTSSRENHDAC8 | |
| SCHEMBL7655882 | 0.78 | CTSS (0.69) | CTSKCTSBCTSSRENHDAC8 | |
| SCHEMBL8977885 | 0.77 | CTSS (0.52) | CTSKCTSBCTSSCAPN1HDAC4 | |
| SCHEMBL9752900 | 0.76 | EPHX1 (0.45) | CTSKCTSBCTSSSIRT5HDAC4 | |
| SCHEMBL4166176 | 0.76 | HDAC4 (0.57) | CTSKCTSBCTSSSIRT5HDAC4 | |
| SCHEMBL9752899 | 0.75 | CNR2 (0.42) | CTSBCNR2CAPN1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | disclosed |