Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 8/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752897 | 0.76 | CTSK (0.47) | EPHX1CTSKCTSBCTSSGABRB1 | |
| SCHEMBL9753260 | 0.72 | EPHX1 (0.41) | EPHX1CTSKCTSBCTSSGABRB1 | |
| SCHEMBL16317891 | 0.72 | PLA2G2A (0.45) | CTSKCTSBCTSSGABRB1GABRB2 | |
| SCHEMBL24415818 | 0.72 | GABRB1 (0.48) | EPHX1CTSKCTSBCTSSGABRB1 | |
| SCHEMBL7289392 | 0.71 | PPARA (0.57) | CTSKCTSBCTSSGABRB1GABRB2 | |
| SCHEMBL5228193 | 0.71 | PPARA (0.57) | CTSKCTSBCTSSGABRB1GABRB2 | |
| SCHEMBL7250898 | 0.71 | PPARA (0.57) | CTSKCTSBCTSSGABRB1GABRB2 | |
| SCHEMBL7655882 | 0.70 | CTSS (0.69) | CTSKCTSBCTSSACEHDAC8 | |
| SCHEMBL9331930 | 0.70 | CTSS (0.69) | CTSKCTSBCTSSACEHDAC8 | |
| SCHEMBL8362256 | 0.70 | GABRB1 (0.52) | CTSKCTSBCTSSGABRB1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | disclosed |