Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7356219 | 0.77 | HTR2A (0.51) | CTSB | |
| SCHEMBL9752897 | 0.75 | CTSK (0.47) | CNR2CAPN1CTSBHDAC3HDAC4 | |
| SCHEMBL9753260 | 0.74 | EPHX1 (0.41) | CAPN1CTSBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL6837920 | 0.74 | MEN1 (0.34) | CYP3A4CYP2C9CYP2C19HDAC1HDAC2 | |
| SCHEMBL9753258 | 0.73 | CNR2 (0.43) | CNR2CAPN1CTSBBACE1CYP3A4 | |
| SCHEMBL9753262 | 0.73 | CNR2 (0.43) | CNR2CAPN1CTSBBACE1CYP3A4 | |
| SCHEMBL9753338 | 0.72 | PPARG (0.42) | CNR2CAPN1CTSBBACE1HDAC3 | |
| SCHEMBL9753335 | 0.72 | PPARG (0.42) | CNR2CAPN1CTSBBACE1HDAC3 | |
| SCHEMBL9644585 | 0.70 | GRIK1 (0.45) | CAPN1CTSBBACE1CYP3A4CYP2C9 | |
| SCHEMBL2544687 | 0.70 | GSR (0.39) | HDAC1HDAC2HDAC6GAALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | disclosed |