Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753338 | 1.00 | PPARG (0.42) | PPARGPPARACNR2PPARDFOLH1 | |
| SCHEMBL9752899 | 0.72 | CNR2 (0.42) | CNR2CAPN1CTSBHDAC3HDAC4 | |
| SCHEMBL3132211 | 0.70 | ALDH1A1 (0.69) | PPARGCNR2HDAC3HDAC4HDAC1 | |
| SCHEMBL23169435 | 0.69 | BACE1 (0.53) | CNR2MCL1BCL2A1BCL2BCL2L1 | |
| SCHEMBL7515480 | 0.69 | SRR (0.56) | FOLH1SRR | |
| SCHEMBL7371689 | 0.67 | ALDH1A1 (0.60) | CNR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL5950448 | 0.67 | BACE1 (0.52) | PPARGPPARACNR2CAPN1CTSB | |
| SCHEMBL5950452 | 0.67 | BACE1 (0.52) | PPARGPPARACNR2CAPN1CTSB | |
| SCHEMBL5950881 | 0.67 | BACE1 (0.52) | PPARGPPARACNR2CAPN1CTSB | |
| SCHEMBL30418055 | 0.67 | MAOA (0.59) | CNR2HDAC1MCL1BCL2A1ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | disclosed |