Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | METAP1 | P53582 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571564 | 0.76 | CYP1A2 (0.56) | CTSBCTSSCTSKMAPTKDM4E | |
| SCHEMBL9752899 | 0.74 | CNR2 (0.42) | EPHX1KIF11ALDH1A1CTSBMAPT | |
| SCHEMBL9752900 | 0.72 | EPHX1 (0.45) | EPHX1SIRT5CTSBCTSSCTSK | |
| SCHEMBL9396778 | 0.71 | GABRP (0.38) | ALDH1A1CTSKGABRB1GABRB2GAA | |
| SCHEMBL9644589 | 0.70 | EPHX1 (0.42) | EPHX1SIRT5KIF11CTSBCTSS | |
| SCHEMBL27905918 | 0.70 | HDAC1 (0.34) | CTSKGAA | |
| SCHEMBL7179037 | 0.69 | ATM (0.39) | ALDH1A1CTSKMAPT | |
| SCHEMBL9364858 | 0.68 | ALDH1A1 (0.47) | EPHX1SIRT5ALDH1A1PPARGPPARA | |
| SCHEMBL7356219 | 0.68 | HTR2A (0.51) | CTSBCTSSCTSKHTR2AHTR2C | |
| SCHEMBL27585538 | 0.67 | SLC7A5 (0.41) | EPHX1CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | disclosed |