Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ICMT | O60725 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752937 | 1.00 | NOD1 (0.48) | NOD1MAPTTHRBBLMCES2 | |
| SCHEMBL4953163 | 0.94 | KDM4E (0.46) | NOD1MAPTTHRBBLMICMT | |
| SCHEMBL4953117 | 0.87 | MAPT (0.48) | NOD1MAPTTHRBBLMTP53 | |
| SCHEMBL19927710 | 0.86 | ICMT (0.53) | NOD1MAPTTHRBBLMCES2 | |
| SCHEMBL9545188 | 0.86 | ICMT (0.53) | NOD1MAPTTHRBBLMCES2 | |
| SCHEMBL9117736 | 0.86 | ICMT (0.53) | NOD1MAPTTHRBBLMCES2 | |
| SCHEMBL9545182 | 0.86 | ICMT (0.53) | NOD1MAPTTHRBBLMCES2 | |
| SCHEMBL9119016 | 0.86 | ICMT (0.53) | NOD1MAPTTHRBBLMCES2 | |
| SCHEMBL19927712 | 0.86 | ICMT (0.53) | NOD1MAPTTHRBBLMCES2 | |
| SCHEMBL11092611 | 0.85 | NOD1 (0.68) | NOD1HDAC2PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008737-A2 | PHARMACOLOGICALLY ACTIVE AMIDE CARBOXYLATE DERIVATIVES | FISONS PLC (GB) | 1991-06-27 | — | — | WO | claimed |