Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744691 | 0.87 | EGFR (0.65) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL27348767 | 0.86 | DHODH (0.47) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL9752865 | 0.85 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL3826301 | 0.80 | GAA (0.53) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL9753402 | 0.77 | MAPK14 (0.46) | EGFRADORA3SLC34A1 | |
| SCHEMBL13860649 | 0.77 | EGFR (0.78) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL3821849 | 0.76 | ALDH1A1 (0.49) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL9753281 | 0.75 | MAPK14 (0.44) | ALDH1A1KMT2AEGFRADORA3LMNA | |
| SCHEMBL14739944 | 0.75 | ALOX5 (0.46) | KDM4EALDH1A1HPGDMEN1GAA | |
| SCHEMBL9753865 | 0.74 | EGFR (0.59) | KDM4EALDH1A1HPGDMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |