Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.37 |
| ▸ | MIF | P14174 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753321 | 0.88 | MAPK14 (0.44) | EGFRALDH1A1ADORA2AKMT2AADORA1 | |
| SCHEMBL9753122 | 0.87 | EGFR (0.38) | EGFRALDH1A1ADORA2AKMT2AADORA1 | |
| SCHEMBL9753124 | 0.87 | EGFR (0.38) | EGFRALDH1A1ADORA2AKMT2AADORA1 | |
| SCHEMBL9753354 | 0.83 | PTGS2 (0.34) | EGFRALDH1A1ADORA2AKMT2AADORA1 | |
| SCHEMBL15070164 | 0.81 | EGFR (0.44) | EGFRALDH1A1ADORA2AKMT2AADORA1 | |
| SCHEMBL8811759 | 0.81 | ADORA2A (0.45) | EGFRALDH1A1LMNAADORA2AADORA1 | |
| SCHEMBL9753040 | 0.80 | PTGS2 (0.36) | EGFRALDH1A1ADORA2AADORA1KCNH2 | |
| SCHEMBL9753160 | 0.77 | MAPK14 (0.41) | EGFRALDH1A1ADORA2AKMT2AADORA1 | |
| SCHEMBL9753157 | 0.77 | MAPK14 (0.41) | EGFRALDH1A1ADORA2AKMT2AADORA1 | |
| SCHEMBL9752941 | 0.77 | ALDH1A1 (0.35) | EGFRALDH1A1ADORA2AADORA1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |