Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753437 | 0.82 | HTT (0.46) | HTTALOX15ALDH1A1 | |
| SCHEMBL9752823 | 0.77 | MAOA (0.44) | NPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30249996 | 0.75 | ALDH1A1 (0.46) | HTTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL14379102 | 0.72 | OPRM1 (0.51) | HTTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL30207602 | 0.72 | — | — | |
| SCHEMBL16993537 | 0.71 | HTT (0.49) | HTTALOX15ALDH1A1 | |
| SCHEMBL17459837 | 0.70 | HTT (0.47) | HTTNPC1RAB9ASMN1; SMN2ALOX15 | |
| SCHEMBL25980736 | 0.69 | KDM1A (0.39) | HTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9977722 | 0.69 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9977775 | 0.69 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991007378-A1 | CYCLOALKYL-SUBSTITUTED GLUTARAMIDE DIURETIC AGENTS | PFIZER LIMITED (GB) | 1991-05-30 | — | — | WO | disclosed |