Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753177 | 1.00 | HRH3 (0.53) | HRH3TRPV6DRD2FKBP1AALDH1A1 | |
| SCHEMBL9739334 | 0.84 | TRPV6 (0.59) | HRH3TRPV6DRD2FKBP1AALDH1A1 | |
| SCHEMBL9668361 | 0.75 | HRH3 (0.50) | HRH3DRD2FKBP1AALDH1A1POLB | |
| SCHEMBL9668366 | 0.75 | HRH3 (0.50) | HRH3DRD2FKBP1AALDH1A1POLB | |
| SCHEMBL9372067 | 0.75 | HRH3 (0.68) | HRH3TRPV6 | |
| SCHEMBL9374317 | 0.75 | HRH3 (0.68) | HRH3TRPV6 | |
| SCHEMBL9372055 | 0.75 | HRH3 (0.68) | HRH3TRPV6 | |
| SCHEMBL9669966 | 0.74 | ALDH1A1 (0.47) | HRH3FKBP1AALDH1A1POLBTSHR | |
| SCHEMBL9376275 | 0.73 | HRH3 (0.65) | HRH3TRPV6 | |
| SCHEMBL9372378 | 0.73 | HRH3 (0.65) | HRH3TRPV6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991010648-A1 | DIPHENYLSULPHOXIMINE MUSCARINIC RECEPTOR ANTAGONISTS | PFIZER LIMITED (GB) | 1991-07-25 | — | — | WO | disclosed |