Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9732422 | 0.77 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2LMNAGAAMEN1 | |
| SCHEMBL9753047 | 0.77 | ALDH1A1 (0.46) | ALDH1A1SMN1; SMN2LMNAGAANPC1 | |
| Hydrochloric Acid SCHEMBL9732362 | 0.77 | GAA (0.53) | ALDH1A1SMN1; SMN2LMNAGAAMEN1 | |
| SCHEMBL9753064 | 0.75 | MMP2 (0.43) | ALDH1A1SMN1; SMN2LMNAGAAMEN1 | |
| Hydrochloric Acid SCHEMBL9753045 | 0.74 | MMP2 (0.42) | ALDH1A1SMN1; SMN2LMNAGAAMEN1 | |
| SCHEMBL4774736 | 0.72 | GAA (0.50) | HTR2AALDH1A1SMN1; SMN2LMNAGAA | |
| SCHEMBL3612322 | 0.69 | GAA (0.49) | HTR2AALDH1A1LMNAGAAMEN1 | |
| SCHEMBL9732427 | 0.67 | ADRB1 (0.54) | ALDH1A1SMN1; SMN2LMNAGAAMEN1 | |
| Hydrochloric Acid SCHEMBL9732368 | 0.67 | ADRB1 (0.55) | ALDH1A1SMN1; SMN2GAAMEN1KMT2A | |
| SCHEMBL28294553 | 0.64 | MEN1 (0.56) | HTR2AALDH1A1SMN1; SMN2LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009023-A1 | N-HETEROARALKYL-SUBSTITUTED 1-ARYLOXY-2-PROPANOLAMINE AND PROPYLAMINE DERIVATIVES POSSESSING CLASS III ANTIARRHYTHMIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-27 | — | — | WO | claimed |