Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP8 | P22894 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9753045 | 0.99 | MMP2 (0.42) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL9753047 | 0.80 | ALDH1A1 (0.46) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL9732366 | 0.78 | ALDH1A1 (0.51) | MMP2MMP9MMP8MMP13MAPT | |
| Hydrochloric Acid SCHEMBL9733184 | 0.77 | GAA (0.52) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL9753181 | 0.75 | HTR2A (0.37) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL29151231 | 0.73 | MMP2 (0.56) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL30354802 | 0.73 | MMP2 (0.56) | MMP2MMP9MMP8MMP13MAPT | |
| SCHEMBL4774736 | 0.72 | GAA (0.50) | MAPTNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL3612322 | 0.69 | GAA (0.49) | MAPTNPC1RAB9ALMNAALDH1A1 | |
| SCHEMBL9732375 | 0.68 | ADRB1 (0.53) | MMP2MMP9MMP8MMP13MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009023-A1 | N-HETEROARALKYL-SUBSTITUTED 1-ARYLOXY-2-PROPANOLAMINE AND PROPYLAMINE DERIVATIVES POSSESSING CLASS III ANTIARRHYTHMIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-27 | — | — | WO | claimed |