Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9739211 | 0.87 | DRD2 (0.56) | DRD2DRD4DRD3LMNAHTT | |
| SCHEMBL9736899 | 0.82 | MAPT (0.43) | DRD2DRD4DRD3LMNARAB9A | |
| SCHEMBL9736462 | 0.77 | KCNH2 (0.58) | DRD2DRD4DRD3LMNARAB9A | |
| SCHEMBL9732661 | 0.73 | RAB9A (0.47) | DRD2DRD4DRD3LMNARAB9A | |
| SCHEMBL28180985 | 0.72 | DRD2 (0.77) | DRD2DRD4DRD3LMNAKCNH2 | |
| Hydrochloric Acid SCHEMBL8055388 | 0.72 | DRD2 (0.97) | DRD2DRD4DRD3LMNARAB9A | |
| SCHEMBL28181096 | 0.70 | DRD2 (0.74) | DRD2DRD4DRD3LMNAKCNH2 | |
| SCHEMBL28180993 | 0.70 | DRD2 (0.74) | DRD2DRD4DRD3LMNAKCNH2 | |
| SCHEMBL28180196 | 0.70 | DRD2 (0.74) | DRD2DRD4DRD3LMNAKCNH2 | |
| SCHEMBL10556391 | 0.70 | HRH3 (0.69) | DRD2DRD4DRD3LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991009023-A1 | N-HETEROARALKYL-SUBSTITUTED 1-ARYLOXY-2-PROPANOLAMINE AND PROPYLAMINE DERIVATIVES POSSESSING CLASS III ANTIARRHYTHMIC ACTIVITY | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-06-27 | — | — | WO | disclosed |