Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD4 | P21917 | 5/20 | 0.38 |
| ▸ | DRD3 | P35462 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9736957 | 0.85 | CYSLTR1 (0.50) | PDE10ACYSLTR2CYSLTR1 | |
| SCHEMBL9753196 | 0.82 | DRD2 (0.56) | MAPTNPC1ALDH1A1RAB9AKMT2A | |
| SCHEMBL9736902 | 0.74 | MAPT (0.45) | MAPTNPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL21674292 | 0.72 | PDE10A (0.55) | MAPTNPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL9732564 | 0.70 | MAPT (0.39) | MAPTNPC1ALDH1A1RAB9AKDM4E | |
| SCHEMBL2022332 | 0.69 | DRD4 (0.62) | NPC1RAB9ADRD2DRD4DRD3 | |
| SCHEMBL9739211 | 0.68 | DRD2 (0.56) | MAPTALDH1A1KDM4EKMT2ADRD2 | |
| SCHEMBL563017 | 0.67 | TDP1 (0.61) | MAPTNPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL8812790 | 0.67 | CHRM2 (0.58) | DRD2DRD4DRD3CHRM2 | |
| SCHEMBL6961128 | 0.66 | DRD4 (0.77) | MAPTNPC1RAB9AKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084463-A | Cardiovascular disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |