Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | CYSLTR1 | Q9Y271 | 7/20 | 0.48 |
| ▸ | CYSLTR2 | Q9NS75 | 6/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753196 | 0.87 | DRD2 (0.56) | DRD2DRD4DRD3LMNAALDH1A1 | |
| SCHEMBL9736957 | 0.82 | CYSLTR1 (0.50) | CYSLTR1CYSLTR2GPBAR1 | |
| SCHEMBL2567854 | 0.82 | LMNA (0.69) | CYSLTR1CYSLTR2LMNAALDH1A1KDM4E | |
| SCHEMBL9737655 | 0.78 | KCNH2 (0.59) | DRD2DRD4DRD3CYSLTR1CYSLTR2 | |
| SCHEMBL10614795 | 0.73 | HDAC1 (0.48) | CYSLTR1CYSLTR2KDM4ECHRM2HTT | |
| SCHEMBL28332341 | 0.73 | HDAC1 (0.45) | CYSLTR1CYSLTR2LMNAALDH1A1GPBAR1 | |
| SCHEMBL28180985 | 0.72 | DRD2 (0.77) | DRD2DRD4DRD3LMNAALDH1A1 | |
| SCHEMBL9732245 | 0.72 | ALDH1A1 (0.43) | DRD2DRD4DRD3CYSLTR1CYSLTR2 | |
| Hydrochloric Acid SCHEMBL8055388 | 0.72 | DRD2 (0.97) | DRD2DRD4DRD3LMNAALDH1A1 | |
| SCHEMBL30388584 | 0.72 | KDM1A (0.50) | CYSLTR1CYSLTR2KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5084463-A | Cardiovascular disorders | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-01-28 | — | — | US | disclosed |