Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753232 | 1.00 | MAPK14 (0.33) | MAPK14PTGS2KDM5BKMT2A | |
| SCHEMBL9753384 | 0.89 | ALDH1A1 (0.36) | MAPK14PTGS2KDM5BKMT2A | |
| SCHEMBL9753008 | 0.82 | PTGS2 (0.32) | MAPK14PTGS2KDM5BKMT2A | |
| SCHEMBL9753006 | 0.82 | PTGS2 (0.32) | MAPK14PTGS2KDM5BKMT2A | |
| SCHEMBL9753157 | 0.80 | MAPK14 (0.41) | MAPK14PTGS2KDM5BKMT2A | |
| SCHEMBL9753160 | 0.80 | MAPK14 (0.41) | MAPK14PTGS2KDM5BKMT2A | |
| SCHEMBL9752987 | 0.78 | HMGCR (0.40) | — | |
| SCHEMBL9752988 | 0.78 | HMGCR (0.40) | — | |
| SCHEMBL9753324 | 0.77 | HMGCR (0.51) | PTGS2 | |
| SCHEMBL9753226 | 0.77 | MAPK14 (0.39) | MAPK14PTGS2KDM5BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |