Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 12/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.34 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9752978 | 0.87 | DHODH (0.41) | GCGRSMN1; SMN2 | |
| SCHEMBL9753309 | 0.81 | MAPK14 (0.43) | GCGRPTGS2 | |
| SCHEMBL27352605 | 0.80 | KDM4E (0.38) | PTGS2NPC1RAB9ASMN1; SMN2CSNK1D | |
| SCHEMBL9753342 | 0.79 | GCGR (0.55) | GCGR | |
| SCHEMBL9752971 | 0.79 | PTGS2 (0.39) | PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9752936 | 0.78 | ALDH1A1 (0.44) | PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9753771 | 0.76 | GCGR (0.40) | GCGR | |
| SCHEMBL9753671 | 0.75 | PTGS2 (0.37) | PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9753676 | 0.75 | PTGS2 (0.37) | PTGS2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9752952 | 0.75 | GCGR (0.39) | GCGRPTGS2CSNK1DCSNK1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |
| CN-1056690-A | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO (JP) | 1991-12-04 | — | — | CN | disclosed |