Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697132 | 0.82 | HSD17B10 (0.54) | HSD17B10TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL19113190 | 0.77 | RAB9A (0.58) | HSD17B10TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL26813752 | 0.73 | HSD17B10 (0.58) | HSD17B10TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL9753404 | 0.71 | GAA (0.47) | HSD17B10TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL22793063 | 0.71 | HSD17B10 (0.44) | HSD17B10TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL24810100 | 0.71 | HSD17B10 (0.68) | HSD17B10TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL9697949 | 0.64 | LMNA (0.54) | HSD17B10TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL20715329 | 0.64 | HSD17B10 (1.00) | HSD17B10TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL2854775 | 0.63 | HSD17B10 (0.57) | HSD17B10TSHRPOLBALDH1A1KMT2A | |
| SCHEMBL1980314 | 0.63 | HSD17B10 (0.57) | HSD17B10TSHRPOLBALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018904-A1 | SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |