Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 5/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.31 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.31 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9753499 | 1.00 | MAPK14 (0.31) | MAPK14MAPK13MAPK12MAPK11KCNH2 | |
| SCHEMBL9752975 | 0.90 | TP53 (0.34) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL9752977 | 0.90 | TP53 (0.34) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL9752941 | 0.89 | ALDH1A1 (0.35) | MAPK14MAPK13MAPK12MAPK11KCNH2 | |
| SCHEMBL9753160 | 0.85 | MAPK14 (0.41) | MAPK14MEN1PDE5AALDH1A1CYP1A2 | |
| SCHEMBL9753157 | 0.85 | MAPK14 (0.41) | MAPK14MEN1PDE5AALDH1A1CYP1A2 | |
| SCHEMBL9753721 | 0.82 | PTGS2 (0.32) | MAPK14MEN1PDE5AALDH1A1CYP1A2 | |
| SCHEMBL9753724 | 0.82 | PTGS2 (0.32) | MAPK14MEN1PDE5AALDH1A1CYP1A2 | |
| SCHEMBL9752932 | 0.80 | PTGS2 (0.34) | MAPK14ADORA2AADORA1 | |
| SCHEMBL9752930 | 0.80 | PTGS2 (0.34) | MAPK14ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991018903-A1 | PYRROLOPYRIDAZINE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-12-12 | — | — | WO | disclosed |