Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 3/20 | 0.57 |
| ▸ | CTSK | P43235 | 2/20 | 0.57 |
| ▸ | CTSB | P07858 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
| ▸ | ACE | P12821 | 1/20 | 0.54 |
| ▸ | CPA1 | P15085 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.54 |
| ▸ | CTSD | P07339 | 4/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9754315 | 1.00 | CTSS (0.57) | CTSSCTSKCTSBMMEACE | |
| SCHEMBL9754243 | 0.88 | CTSD (0.62) | CTSSCTSKCTSBMMEACE | |
| SCHEMBL9754245 | 0.88 | CTSD (0.62) | CTSSCTSKCTSBMMEACE | |
| SCHEMBL5630007 | 0.87 | CTSS (0.69) | CTSSCTSKCTSBACEKLK5 | |
| SCHEMBL31584535 | 0.87 | CTSS (0.69) | CTSSCTSKCTSBACEKLK5 | |
| SCHEMBL5844919 | 0.84 | CTSS (0.64) | CTSSCTSKCTSBMMEACE | |
| SCHEMBL9754222 | 0.81 | REN (0.54) | MMEACECPA1ACE2REN | |
| SCHEMBL9754227 | 0.81 | REN (0.54) | MMEACECPA1ACE2REN | |
| SCHEMBL7377285 | 0.81 | REN (0.56) | CTSSCTSKCTSBCTSDELANE | |
| SCHEMBL7377290 | 0.81 | REN (0.56) | CTSSCTSKCTSBCTSDELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991008221-A1 | PEPTIDE INHIBITORS OF HIV PROTEASE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1991-06-13 | — | — | WO | disclosed |