Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.36 |
| ▸ | NMT1 | P30419 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474617 | 0.80 | MAPT (0.52) | EDNRAMCL1MAPTMAPK1KDM4E | |
| SCHEMBL11194764 | 0.76 | EDNRA (0.43) | EDNRAMCL1MAPTKDM4ENPC1 | |
| SCHEMBL2773751 | 0.73 | MCL1 (0.58) | MCL1MAPTMAPK1KDM4ENPC1 | |
| SCHEMBL3612625 | 0.71 | RAB9A (0.68) | MAPTKDM4ENPC1RAB9AMEN1 | |
| SCHEMBL12760838 | 0.71 | ALDH1A1 (0.42) | KDM4EMEN1KMT2ATSHRLMNA | |
| SCHEMBL17669713 | 0.71 | L3MBTL1 (0.55) | MCL1MAPTMAPK1KDM4ENPC1 | |
| SCHEMBL5279040 | 0.70 | EDNRA (0.62) | EDNRAMCL1MAPTKDM4ENPC1 | |
| SCHEMBL5273001 | 0.70 | CAPN1 (0.56) | MCL1MAPTMAPK1KDM4EBCL2 | |
| SCHEMBL4672803 | 0.70 | MCL1 (0.54) | EDNRAMCL1MAPTMAPK1KDM4E | |
| SCHEMBL1474620 | 0.69 | GABRA1 (0.47) | EDNRAMCL1MAPTMAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991014688-A1 | HETERO POLYCYCLIC BIOCIDAL COMPOUNDS AND THEIR USE IN MEDECINE | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-10-03 | — | — | WO | disclosed |
| EP-0447703-A1 | Hetero polycyclic biocidal compounds, their synthesis and intermediates therefor,formulations containing them and their use in medicine | THE WELLCOME FOUNDATION LIMITED (GB) | 1991-09-25 | — | — | EP | disclosed |