Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KAT2B | Q92831 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4295085 | 0.86 | MAPT (0.63) | PRSS1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL37830 | 0.86 | MAPT (0.63) | PRSS1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL29928397 | 0.86 | MAPT (0.63) | PRSS1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL9755054 | 0.84 | MAPT (0.65) | PRSS1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL28252139 | 0.84 | MAPT (0.68) | PRSS1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL9820097 | 0.82 | PRSS1 (0.57) | PRSS1MAPTTDP1HCAR3L3MBTL1 | |
| SCHEMBL4359815 | 0.81 | MAPT (0.63) | PRSS1MAPTKMT2AMEN1TDP1 | |
| SCHEMBL19972855 | 0.81 | HCAR3 (0.66) | PRSS1MAPTHCAR3KAT2BLMNA | |
| SCHEMBL8804352 | 0.81 | PRSS1 (0.54) | PRSS1MAPTHCAR3L3MBTL1KAT2B | |
| SCHEMBL4301793 | 0.80 | MAPT (0.70) | PRSS1MAPTKMT2AMEN1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340087-B1 | USE OF INTRAMOLECULARLY, COVALENTLY CROSS-LINKED PROTEINS AS BINDING PARTNERS IN IMMUNOASSAYS | ROCHE DIAGNOSTICS GMBH (DE) | 2012-05-30 | — | — | EP | claimed |