Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASE1 | P07998 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 9/20 | 0.38 |
| ▸ | TK2 | O00142 | 7/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064864 | 0.90 | RNASE1 (0.38) | RNASE1TK1TK2MAPK1HPGD | |
| SCHEMBL6301637 | 0.86 | RNASE1 (0.37) | RNASE1TK1TK2MAPK1 | |
| SCHEMBL6756343 | 0.83 | RNASE1 (0.36) | RNASE1TK1TK2MAPK1 | |
| SCHEMBL29834207 | 0.80 | SLC28A1 (0.35) | — | |
| SCHEMBL6753651 | 0.80 | RNASE1 (0.35) | RNASE1TK1TK2MAPK1 | |
| SCHEMBL27791482 | 0.79 | TK1 (0.40) | TK1TK2 | |
| SCHEMBL1706308 | 0.78 | RNASE1 (0.39) | RNASE1TK1TK2HPGD | |
| SCHEMBL6474433 | 0.78 | TOP2A (0.33) | RNASE1TK1TK2 | |
| SCHEMBL27043055 | 0.77 | TK2 (0.39) | TK1TK2 | |
| SCHEMBL28282990 | 0.77 | RNASE1 (0.38) | RNASE1TK1TK2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991004983-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1991-04-18 | — | — | WO | disclosed |