Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAD52 | P43351 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9755466 | 0.89 | KDM1A (0.42) | KDM1AKMT2APOLBRAD52PDGFRB | |
| SCHEMBL9755380 | 0.89 | POLB (0.47) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755438 | 0.83 | KDM1A (0.53) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755338 | 0.83 | KDM1A (0.53) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755378 | 0.80 | KDM1A (0.44) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755321 | 0.75 | ACHE (0.47) | KDM1AKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL9592698 | 0.74 | KDM1A (0.53) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9594446 | 0.74 | HDAC1 (0.54) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9755355 | 0.74 | KDM1A (0.50) | KDM1AKMT2APOLBRAD52GFER | |
| SCHEMBL9595260 | 0.74 | TOP2A (0.58) | KDM1AKMT2APOLBRAD52GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991005770-A1 | POTENTIAL ANTICANCER AGENTS DERIVED FROM ACRIDINE | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-05-02 | — | — | WO | disclosed |